SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0442c6bd41f99979b8c82d979886daf4840720974ff98286bc83613a3b199d12' 
  AND token = 'YTqn3GRNtdrEfyNqcdGe+g1pCLyw+IMMhZORDFaYAmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}