SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0edd10e1b66a39e54098ad17dc2af413e8424f372f87da26660ded8c7bde67e' 
  AND token = 'n15rtdGKXCTlr+sFLHuG9vq5hJTR9F74V+MEo0jAMAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}