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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d8fe0e79f51b287808c61a3268bcaed443fec226a5cf192e217467f7fd0c44' 
  AND token = 'XCY+E33OwG9fBYHpdY+ayHr1aNNailSpmsfoZSmV3Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}