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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46464eb43271b7eee6ab5a60ac95871f403862c6e3fc3fec9f6962f80e2b39a6' 
  AND token = 'QA5BO7dbYw96vD5rJ6evMQvfYVlfWhqppJAenDf5KeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}