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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4b92f3d8d88b0a02b2778fbe88a6d65f883fba6c7f66595ac019be632c6a53' 
  AND token = '19F1OFe9Ol1EyT3JMUL+qs0jZ57AtWxyqWe+HuvRnW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}