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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100f2f928702d8a8c05b6c08250b141643134e1bcf2122cf8bef7cf74662cbdb' 
  AND token = 'lTxY5FzhOisiLILfQ17LQ+u0fvKEnKeLO7qY1R7+l4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}