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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b274a9aba9b6bd9a20d0f7a0ddeacff06d605dd7bfcccb75c1e25995d198903' 
  AND token = 'FGWfT8u7z8KlxgHL7o5HvgvarUySyKwpXDXaxF6Jhno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}