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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21aadaafafcd343d2daeb59ad3a98f35146dbd9295bb431cf386351b640e64d9' 
  AND token = 'lnwE6L+pv/TkN2KGl2j4KplDiWcbFO3DpaalrR+CzJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}