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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9035416c338f1d20c4d437bf763cca73f23b7881e2d8c6168c678b224c5237cb' 
  AND token = 'NiXRCZ6alnER+hVyVcPCuAu7a3aoW6Tt5PpI1dzAJyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}