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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43a2557c532d641c2d81d59e6a22dedabb3e73e1914126e01f032089aec92b8' 
  AND token = '3/AISEYnxkxqPU5r24l/hOEvuTf55itbR+jMwr//CgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}