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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f9beaf17ac8dc717856cea30d68a8cc420c73c5493efc3f4d5922bc8efe0efd' 
  AND token = 'Ycp0P30UAhnAZ4YsA1sArhHmDSyEdOUgzzMluOOBA2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}