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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce53540197e69bd8f53f0ff81a006dd3d21350e081a195a82f1f6c2b1712d055' 
  AND token = 'hMCymtrN5Lla8NuwFcWh09LQl4E15mzVbv1BLp3Fyu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}