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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309df593a2f23b5abfd4bed8b33025a2739ea6090fc2c77f3910506e35a8c1fe' 
  AND token = '8KUMJSTox8mpqiSkigg/rYQbY5/oLdM7EMUWvvZqWKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}