SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e854991fd4fd657d2150ffd3068128bdedaa66087c8c0488d2fe2ab81b45df' 
  AND token = 'rlnRnW50jAml1PCiHJqBf5G28JZwQyPUOZTykND+B5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}