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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '802c601b6a78a3c4ac15f86284dfc957868548c21b26f08bfcfc4c788ebe2b1b' 
  AND token = 'ujEo32uhVRg2QTLE5X9Z/X7XNsomOjKQcIcXfDQEWxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}