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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a5fe06d6205ec4caa5c38db3c804682a1999254a2020e0d57073e5268318d7' 
  AND token = 'FSv4Ztdjg3rgy52JwACtNY75gsYvnn7SdxVffy0VocI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}