SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5603746730816570de0799bd12d83d904953bf52ac90c5450280d2128ddb4f2' 
  AND token = 'EIX6lZQbx383xNFZcO0+HlEa6DWxZYL3Rnf0JinH3gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}