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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f746cfa26b898ffc1be291927f5e3c1e829e3fe677eccdd0444130a7b4fb01e6' 
  AND token = 'k1mm30D68CJZtc09X2LwsTkd87+y3SFdtoExTK2IQRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}