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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2013069e0072bfe27b3bff0aee03aaea3079e4fb19b5b9658c780b780c4a3d4a' 
  AND token = 'kVwEu2nfb3/DEKnjh8DTG7wgvvBOUVtYEHTtlwFJav8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}