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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd2aa6d25ca210659b5a91b90e5bba96d656deacc2984422d745d42610da12b' 
  AND token = '5J1Fs2VVAIHRCCsgXRYeJ4ekdweYy+sPiycl7orTBkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}