SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '839b17011e6d1c492f4ed6b7533ba1af0a4149d616e1256818bbe509ffe261c1' 
  AND token = 'sI5tE30BuDOJ0BWOp6nuv7+0GPZ4PmDWhMyF/C/dPws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}