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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20faa5792c091d703666eb274074577e899e15a067170262732ef99043457290' 
  AND token = 'PbJDJ3T/BGSLRyYCUP4wU5kFdPuam63X0EJU2NJvbJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}