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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a8435f34767abed1a8b4f05bb3813395d3fc49b49fe76139f8c2d4a6bcb3e6' 
  AND token = 'alnd3N+Cge2G44JaC4oY6z58jzIjkZxftxVSlLLIGsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}