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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c81dea7f0dc3fb4a98a013fc30b85acc382fd28bbc7bc8df0a925bd66150e1a' 
  AND token = 'PP8xMSi2LWfJo05qRuQ/wOaEF8UZYwc7bh1t3DT/20g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}