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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '293eef45b3f5c1e40a0c7db8788bc26a233161b94e1b67a2b44f97f7380d5940' 
  AND token = 'w8T5vpPORMkY3FyhtzSA4oZfbM17anNHyLonbBqD6sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}