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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce2735cf325b9ae3bc370f3d8f00fa1c214bf27c643cc2946d9066326c3d6f3' 
  AND token = 'n/+YsR5+tWJ7RcC/Qkyy/a19iCU7c27vscFO/h7yQfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}