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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6dfadbc92182979d8d51bb4c1da322fa320b5af200294972086c046c1b0ac4' 
  AND token = 'xMe7vKF5NCQQppCAOI+0VV7/Y+VYyJGE1SbEO1GgUhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}