SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e102d45e9c7d2f5995ff8b2a63fbfd2bc46b03a108bcb780c8ef073b3c166be8' 
  AND token = '4Y00jyg1sz9/OX/quDm+s41b+1FTiH1L1cenGXldVNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}