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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e521d3460b762b846067b17f9ff8a2693a6a4b411695eea6eea924905ea965' 
  AND token = '3QBDi/Zo7RVcdqtTVGjCN2CMEAihCTvaUbSsowEQ4dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}