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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4b88052cef049d4ec95a2a7577990c1ed2ba7eb165c048de377caa856743bc' 
  AND token = 'fLeQgP3P4Fj+JKrh5VDxb5KfZFQZN8gRFA03dzcuock=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}