SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b41724f8ce093e16959a4680d2febbc6b7756e52e77778daadf7b58d21a47d6' 
  AND token = '/t6IGOfeJdTQxPmoRfvsVM5L5UbNhnghOxEKOcnw9q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}