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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cee2649b7b6af5baa664790c8f437055c245c1b7bc327be0141b32d470c4e7a4' 
  AND token = '1aLv3kKbe/k3LdNXCRPRKS20lEUwTlYBLxxa41nRMWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}