SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd8a5f8942d320a3cd5c65cadaee8f3688f913fad174275d0324657b36b1736f' 
  AND token = 'oSG08wv55gOw3QTGoEMfedHm28z2aKnAlRIpRfLdMyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}