SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea91216133e7027269315c11d236c5c8ed092c883b0afbca198b061178bf3372' 
  AND token = '6RMPU78O3tznH4hRQAZZkuVOvMip7G7gZqQ0OyTUEDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}