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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81510639e08cffe447e0567987d29975e342770fb521a8b35153ba0dd7d57149' 
  AND token = 'EJ9x0eLK0GiJfOOt+dkcxhquUWPLd1GmMzjAR5pHe38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}