SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '846e6b74dff68ec1f3b900057468622f7f33ac40d3706fa37052ae8d43ce04a5' 
  AND token = 'RlnUhEXnJKi9y2XdVmhR/eKFQMWY7vDgeA6ZcDKtJjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}