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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '475fdaed2438819569e57e99f6b4d59f835e24177db1dff0172ca201380282b0' 
  AND token = 'ob6aqdL4vo0k4qVGFxENA+nzuqPuIKQ8LPz6OTnWCoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}