SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c39a7bf63695d5b26c36979e5f2b086b46391878c8872ac37b0a28eb702da1b6' 
  AND token = '6EyLIABgHbTOA3F8+w05Zcaly6yg2BBO4sTu9C41PgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}