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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df684c638ab1d85501a12c2667270cdbee66a4a240d3dd1bace42ff56701fefb' 
  AND token = 'TdsiSASJRGm29JfcW1yaZ96zaCZY2dWxzR8hV7/2YKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}