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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef9c906b094dfe16ff13b16bef1c1ce963d637ca22d422434270c4631d77303' 
  AND token = 'u40EI/oK+2l81XRuueNR12WSjo4/CsP/JrMLvBY40X0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}