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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c3a296c5148defeebb7f594f78ca628b07f794ef3bd8ff3023d756e6fe6fd1d' 
  AND token = 'IznJbMLZaDFNAmsf/ZhoFR2Av8BPsObSY5De5VDXhLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}