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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b63c96cb278b199bbdc83c4659c53c6602861b857a09e9acd7cbca7f95cb91' 
  AND token = '41PIhbupOHApNs+1T2gkWHWFgP/PbYZq4g2QiywVT/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}