SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0162a75ab650ebc78089d4266ecd41e261a72cd7bcc6f0e100a86528ba595f85' 
  AND token = 'BUbzq0ACxjf/8lCm+j6hnyXYvHqrBazj2DLvOfLfPdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}