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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb011f089a1ed23e1028395974565bf666eb34754f5abba3d8dbc4aaef61a2b' 
  AND token = '/Ro29UAeWsrVz2D2cWH7H5Auo9YIsEOI9AM34d13GUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}