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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d70bfa607a13788021257c6aca6e9b45915b984691a97f2999f90f04bb3994' 
  AND token = 'JNEG5bIE5QzSUZ1/BO4k6C8RStZz7XrR2Q8fSQo52nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}