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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4edb44bcc6e68892f080c4bd220c891de07ae075ca51efb3ef64d07ff4dc9304' 
  AND token = 'X/Hg08cSQ11+FhbK2AD4hwYjd8zfoYk5uTFHRK5Cyb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}