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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff3b84bbc70dfc13d59e74f35df8107566075329d5b4737e7b41744e197b6c14' 
  AND token = 'xo5Kmx6t0EKcfpUHNOnsAruHo7LUbb2pv40bXKRuSbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}