SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066a54438543692794cda66edfad2ffdad32af4ccdc3e4a2f87f95406f1c4472' 
  AND token = 'dVXBj7bqcv8Gyv+F5fy+2vNp9A6Q8ae6gUQBIj6F0N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}