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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cab0fb2898461878e7d3a543bb9c8531c6162d6f22a48dac0b5c209225d27db' 
  AND token = '6NhiE6m48iH4VumlqRC/8dm5GoMFl9H96F9YgOb1Du4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}