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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f2f1ae0d0c6e65958390dbe24aceee8f7b28278fdefcdd555132a89ca1918d2' 
  AND token = '0Hsn6aM38gHj9vf+ePjxfGYKCDLRV7z5stjbwkYhkNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}